Dry Mouth| Causes| Consequences |Prevention |Treatments
- Dr Abi
- Apr 25, 2023
- 7 min read
Updated: Aug 6, 2023
A dry mouth, or xerostomia, is a condition that results from reduced or absent saliva flow in the mouth. Saliva plays a vital role in maintaining oral health by lubricating the mouth, protecting teeth from decay, and aiding in digestion.

Dry Mouth : Prevention, Treatments
The mechanism behind saliva
Saliva production is regulated by the autonomic nervous system, specifically the parasympathetic nervous system. The parasympathetic nervous system is responsible for stimulating saliva production through the release of acetylcholine, which activates muscarinic receptors on the surface of salivary gland cells. A decrease in acetylcholine activity or damage to the salivary glands can lead to a decrease in saliva production and, thus, dry mouth.
Role of Saliva
Saliva is important for maintaining oral health and function. It performs several essential functions in the mouth, including:
1. Lubrication and Moistening: Saliva helps to lubricate and moisten the oral mucosa, making it easier to speak, chew, and swallow.
2. Digestion: Saliva contains enzymes, such as amylase, that help to break down carbohydrates in food, aiding in the digestive process.
3. Protection against Dental Decay: Saliva helps to neutralize and wash away acids produced by bacteria in the mouth, reducing the risk of dental decay.
4. Antibacterial Properties: Saliva contains antibodies and other antimicrobial components that help to protect against oral infections.
5. Wound Healing: Saliva contains growth factors and other components that promote wound healing in the mouth.
6. Taste Perception: Saliva helps to dissolve and distribute flavors and tastes throughout the mouth, enhancing taste perception.
Overall, saliva plays a crucial role in maintaining oral health and function. Reduced saliva flow, such as in the case of dry mouth or xerostomia, can lead to a range of oral health problems, including dental decay, gum disease, oral infections, difficulty speaking, and swallowing.
Causes of Dry Mouth
1. Damage to the salivary glands
Salivary gland damage can be due to radiation therapy, chemotherapy, surgery, or infection. This can result in a reduction in the quantity and quality of saliva produced.
2. Medications
A number of medications can cause xerostomia as a side effect by interfering with the autonomic nervous system or affecting the function of the salivary glands. These medications include antihistamines, decongestants, antidepressants, antipsychotics, and muscle relaxants.
3. Medical conditions
Xerostomia can be a symptom of several medical conditions, including Sjogren's syndrome, diabetes mellitus, hypothyroidism, HIV/AIDS, and sarcoidosis. These conditions can cause damage to the salivary glands, alter the composition of saliva, or interfere with salivary gland function.
4. Neurological disorders
Neurological disorders such as Parkinson's disease, stroke, and multiple sclerosis can affect the nerves that control the salivary glands, leading to decreased saliva production.
5. Autoimmune disorders
Autoimmune disorders such as Sjogren's syndrome, systemic lupus erythematosus, and rheumatoid arthritis can cause inflammation of the salivary glands, leading to decreased saliva production.
6. Aging
As individuals age, there is a decrease in the number of functional salivary gland cells, leading to decreased saliva production.
7. Lifestyle factors
Lifestyle factors such as smoking, alcohol consumption, and caffeine intake can contribute to xerostomia by affecting salivary gland function and saliva composition.
Common diagnostic methods for dry mouth
1. Medical history: Your healthcare provider will ask about your symptoms, medical history, and any medications you may be taking that could be contributing to your dry mouth.
2. Physical examination: A physical exam of your mouth, teeth, gums, and throat may be performed to assess the extent and severity of the dryness. Also, check for signs of infection or inflammation in and around oral cavity.
3. Saliva testing: Saliva testing can measure the amount and quality of saliva being produced. This may involve collecting saliva samples or performing a salivary flow rate test.
4. Blood tests: Blood tests may be ordered to check for underlying medical conditions that could be contributing to the dry mouth or xerostomia, such as diabetes or Sjogren's syndrome.
5. Imaging tests: Imaging tests, such as ultrasound or MRI, may be ordered to evaluate the salivary glands for damage or obstruction.
6. Biopsy: In some cases, a biopsy of the salivary glands may be performed to evaluate for signs of inflammation or infection.
consequences of dry mouth
1. Oral infections
Saliva plays an important role in protecting the mouth against bacterial and fungal infections. Without adequate saliva, the risk of oral infections such as candidiasis (oral thrush) or bacterial overgrowth increases.
2. Tooth decay
Saliva helps to neutralize acids in the mouth and remineralize tooth enamel. A lack of saliva can lead to an increase in the acidity of the mouth, which can result in tooth decay.
3. Gum disease
Saliva helps to clean the mouth and remove plaque from the teeth and gums. A lack of saliva can lead to the buildup of plaque and an increased risk of gum disease.
4. Bad breath
Saliva helps to rinse away bacteria and food particles that can cause bad breath. A dry mouth or xerostomia can lead to chronic halitosis (bad breath).
5. Difficulty speaking and swallowing
Saliva helps to lubricate the mouth, making it easier to speak and swallow. A dry mouth or xerostomia can make these activities difficult and uncomfortable.
6. Nutritional deficiencies
Saliva plays a role in the digestion and absorption of food. A lack of saliva can lead to difficulty chewing and swallowing, which can result in malnutrition and weight loss.
7. Decreased quality of life
Chronic dry mouth or xerostomia can lead to discomfort, embarrassment, and a decreased quality of life.
Treatment options for dry mouth
1. Addressing underlying medical conditions
If dry mouth or xerostomia is caused by an underlying medical condition, such as Sjogren's syndrome, diabetes, or HIV/AIDS, treating the condition may help to alleviate the dry mouth symptoms.
2. Medication adjustments
If dry mouth or xerostomia is caused by medications, adjusting the dosage or switching to a different medication may help to alleviate the symptoms. However, it is important to consult with a physician before making any changes to medication.
3. Saliva substitutes
Artificial saliva products can help to moisten the mouth and alleviate dry mouth symptoms. These products come in a variety of forms, including sprays, gels, and lozenges. See the dry mouth : prevention, treatments with saliva substitute products at the end.
4. Prescription medications
Prescription medications, such as pilocarpine and cevimeline, can stimulate the salivary glands and increase saliva production.
5. Lifestyle modifications
Making lifestyle modifications such as avoiding tobacco and alcohol, drinking plenty of water, and avoiding spicy or acidic foods may help to alleviate dry mouth symptoms.
6. Dental care
Regular dental checkups and cleanings are important for maintaining good oral health. Your dentist may also recommend the use of fluoride treatments or prescription toothpaste to help prevent tooth decay.
Prevention of dry mouth
1. Stay hydrated
Drinking water helps maintain the salivary flow rate and increases salivary volume. Saliva plays an important role in lubricating, cleansing, and protecting oral tissues, so maintaining a good level of hydration can help prevent dry mouth.
2. Avoid mouth-breathing
Mouth-breathing can result in increased evaporative water loss from the oral cavity, leading to dry mouth or xerostomia. Breathing through your nose helps humidify the air before it reaches the oral cavity, helping to keep the mouth moist.
3. Limit caffeine and alcohol intake
Caffeine and alcohol have diuretic effects, which can cause the body to lose water and contribute to dehydration. Dehydration can lead to dry mouth, so it's important to limit your intake of these substances.
4. Avoid tobacco use
Tobacco use can lead to dry mouth or xerostomia, as well as a host of other oral health problems, such as gum disease and oral cancer.
5. Use a humidifier
A humidifier can add moisture to the air, helping to prevent dry mouth caused by dry indoor air.
6. Practice good oral hygiene
Brushing and flossing your teeth regularly helps remove bacteria and plaque from your mouth, which can contribute to dry mouth and other oral health problems.
7. Consider medication side effects
Many medications can cause dry mouth as a side effect. If you are taking medication and experiencing dry mouth, talk to your physician about possible alternatives or solutions.
8. Chew sugar-free gum or suck on sugar-free candy
Chewing gum or sucking on candy can stimulate salivary flow, helping to keep the mouth moist. Sugar-free options are recommended to prevent dental decay.
Types of saliva substitutes
Dry Mouth treatments with saliva substitute are-
1. Sprays
Saliva substitute sprays come in a spray bottle and are used to moisturize the dry mouth. These sprays typically contain glycerin, which helps to lubricate the mouth and throat.
Examples are:-
-Salivary Artificial saliva mouth spray

-Mouth Kote Dry Mouth Spray

-E-Saliva Plus Mouth Spray

-West Coast Owet Solution Dry Mouth Moisturizer spray

2. Gels
Saliva substitute gels are thicker than sprays and can provide longer-lasting relief. These gels typically contain a combination of glycerin and carboxymethylcellulose, which helps to coat the mouth and throat.
Examples are:-
-GC Dry Mouth Gel

-Biotene Oral Balance Dry Mouth Moisturizing Gel

3. Lozenges
Saliva substitute lozenges are designed to dissolve slowly in the mouth, releasing moisture and providing relief. These lozenges typically contain xylitol, which can help to prevent tooth decay.
Examples are:-
-Act Dry Mouth Mint Lozenge

4. Chewing gum
Chewing gum can help to stimulate saliva production and alleviate dry mouth symptoms. Sugar-free chewing gum is recommended to prevent tooth decay.
Examples are:-
-Brahmosmi's DRIMOUTH Chewable Tablets

-Xylimelts For Dry Mouth strips

5. Mouthwashes
Mouthwashes designed for dry mouth can help to moisturize the mouth and freshen breath. These mouthwashes typically contain a combination of moisturizers and antibacterial agents.
Examples are:-
-ICPA Wet Mouth Mouthwash

-Dr. Dentaids Saleva Mouthwash

-Biotene Dry Mouth Mouthwash

-Oralvit Oral Rinse Dry Mouthwash

In conclusion, dry mouth, also known as xerostomia, is a condition that can have a significant impact on oral health and quality of life. It is characterized by reduced or absent saliva flow in the mouth, which can lead to a range of oral health problems such as dental decay, gum disease, and oral infections.
Therefore, managing dry mouth is essential to maintain good oral health and function, and this may involve addressing the underlying cause, using saliva substitutes, or other therapeutic interventions. By recognizing the importance of saliva and managing dry mouth effectively, individuals can ensure optimal oral health and quality of life.
Author-

Dentist
10 + years of experience
Certification in Practical Implantology
Certification in Rotary Endodontics
Associate Fellowship in Laser Dentistry Certification in Laser Treatments Diploma in Practical Occlusion and Restorative Dentistry Course Advanced occlusion appliance therapy, TMD Comprehensive Course in Veneers - Ceramic & Composite Aesthetic Certified - Europe, Germany WHO Health Program Certified Certification in Laser Dentistry Fellow of the Academy of General Education (FAGE) Member of the Indian Dental Association (IDA)

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