Toothpaste- New ingredients
- Dr Abi
- May 11, 2023
- 4 min read
Updated: May 23, 2023
Toothpaste is an essential part of oral hygiene, and over the years, manufacturers have been constantly innovating and adding new ingredients to their formulations. The latest research and articles in the field of toothpaste ingredients highlight the importance of natural ingredients and the use of CPP-ACP, Tricalcium phosphate, probiotics, enzymes, and hydroxyapatite to promote healthy teeth and gums.
Hydroxyapatite
Hydroxyapatite is a naturally occurring mineral that makes up the majority of tooth enamel, and has been gaining popularity as an ingredient in toothpaste.
Recent studies have shown that toothpaste with hydroxyapatite can be as effective as fluoride toothpaste in reducing cavities and tooth sensitivity.
In addition, hydroxyapatite has been found to help remineralize teeth and repair early-stage tooth decay.
A recent article in the Journal of the Indian Society of Pedodontics and Preventive Dentistry concluded that toothpaste containing hydroxyapatite has "a promising future as a biocompatible, effective, and safe alternative to fluoride toothpaste."
Tricalcium phosphate (TCP)
TCP is a calcium-based compound that has been shown to have benefits for oral health, including strengthening tooth enamel and reducing the risk of tooth decay.
TCP works by promoting the remineralization of tooth enamel, which is the process by which minerals such as calcium and phosphate are restored to the surface of teeth. This helps to strengthen tooth enamel and make it more resistant to decay.
Studies have shown that toothpaste containing TCP can be effective in reducing the risk of cavities and improving overall oral health.
A study published in the Journal of Clinical Dentistry found that toothpaste containing TCP was effective in reducing the incidence of new cavities in children.
Another study published in the Journal of Dental Research found that toothpaste containing TCP was effective in reducing tooth sensitivity.
Casein phosphopeptide-amorphous calcium phosphate(CPP-ACP)
(CPP-ACP) is another ingredient that has gained attention in recent years for its potential benefits in oral health.
CPP-ACP is a bioactive milk protein that is able to bind to calcium and phosphate ions, which are essential for the remineralization of tooth enamel.
When CPP-ACP is added to toothpaste formulations, it can help to reduce the risk of tooth decay by promoting the remineralization of tooth enamel.
Studies have shown that toothpaste containing CPP-ACP can be effective in reducing the incidence of new cavities and improving overall oral health.
In addition to its remineralization benefits, CPP-ACP has also been shown to have antibacterial properties, which can help to reduce the levels of harmful bacteria in the mouth.
This is important because harmful bacteria in the mouth can contribute to the development of tooth decay and gum disease.
Overall, CPP-ACP is a promising ingredient for toothpaste formulations, and its use is likely to continue to grow in the coming years as more research is conducted.
Xylitol
Xylitol, a natural sweetener derived from plant sources, has also been shown to have significant benefits for oral health.
Studies have demonstrated that xylitol can reduce the number of bacteria that cause tooth decay in the mouth.
Toothpaste formulations that include xylitol can help promote healthy teeth and gums and reduce the risk of cavities.
Enzymes
Enzymes such as papain and bromelain are being added to toothpaste formulations to provide a more thorough cleaning than toothpaste alone can offer.
These enzymes help break down food particles and plaque on teeth, providing a more effective clean.
According to a recent study in the Journal of Indian Society of Periodontology, toothpaste containing papain and bromelain was more effective at reducing plaque and gingivitis than toothpaste without these enzymes.
Probiotics
Probiotics are another new addition to toothpaste formulations that have shown promising results for promoting healthy teeth and gums.
Recent research has demonstrated that probiotics can help balance the oral microbiome, reducing the risk of cavities, gum disease, and bad breath.
A study published in the Journal of Indian Society of Pedodontics and Preventive Dentistry found that toothpaste containing probiotics reduced the number of bacteria that cause tooth decay and gum disease.
In conclusion, the latest research and articles in the field of toothpaste ingredients highlight the importance of natural ingredients and the use of hydroxyapatite, xylitol, enzymes, and probiotics to promote healthy teeth and gums.
These innovative ingredients offer safe and effective alternatives to traditional toothpaste formulations and can help reduce the risk of cavities, gum disease, and other oral health problems.
As always, it's important to consult with a dentist and choose a toothpaste that meets your individual needs and preferences.
Reference
1. Remineralization Potential of Nanohydroxyapatite Toothpaste Compared with Tricalcium Phosphate and Fluoride Toothpaste on Artificial Carious Lesions, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007336/
2. Xylitol in preventing dental caries: A systematic review and meta-analyses
3. Anti-plaque and anti-gingivitis effect of Papain, Bromelain, Miswak and Neem containing dentifrice: A randomized controlled trial
4. Efficacy of Extrinsic Stain Removal by Novel Dentifrice Containing Papain and Bromelain Extracts
5. 6. Harrison JWE, Salisbury GB, Abbott DD. Effect of enzyme toothpastes upon oral hygiene. J Periodontol. 1963;34:334–7. [Google Scholar]
6. Role of probiotics and synbiotics on inhibiting Streptococcus mutans level in saliva of children A randomized controlled trial, Journal of Indian Society of Pedodontics and Preventive Dentistry
7.Evaluation of the Effect of Probiotic Bacillus coagulans Unique IS2 on Mutans Streptococci and Lactobacilli Levels in Saliva and Plaque: A Double-Blind, Randomized, Placebo-Controlled Study in Children
8. Recent Advances in Dental Hard Tissue Remineralization: A Review of Literature
9. Enhancing Fluoride Mediated Dentine Sensitivity Relief through Functionalised Tricalcium Phosphate Activity
10. Effect of CPP-ACP Paste on Dental Caries in Primary Teeth
11. Effectiveness of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) Compared to Fluoride Products in an In-Vitro Demineralization Model
12.The use of hydroxyapatite toothpaste to prevent dental caries
13. Comparative efficacy of a hydroxyapatite and a fluoride toothpaste for prevention and remineralization of dental caries in children
14. Hydroxyapatite in Oral Care Products—A Review
Author-
Dr. Abi Negi
Dentist
10 + years of experience
Certification in Rotary Endodontics
Associate Fellowship in Laser Dentistry Certification in Practical Implantology
Certification in Laser Treatments Diploma in Practical Occlusion and Restorative Dentistry Course Advanced occlusion appliance therapy, TMD Comprehensive Course in Veneers - Ceramic & Composite Aesthetic Certified - Europe, Germany WHO Health Program Certified Certification in Laser Dentistry Fellow of the Academy of General Education (FAGE) Member of the Indian Dental Association (IDA)
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